Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Health Network, Toronto
About this trial
This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.
Eligibility criteria
Qualifiers
Receiving a respiratory support modality as a bridge to lung transplantation
Formally listed for transplantation
Disqualifiers
Previously diagnosed with neuromuscular disorder
Received invasive mechanical ventilation for >48 hours in the preceding four weeks
Thoracic cage deformity
Trial design
Treatments tested in this trial
- Respiratory support
Treatment groups
40 Participants
are divided into 3 treatment groupsSponsors and collaborators
University Health Network, Toronto
Lead sponsor
The Hospital for Sick Children
Collaborator
Source ClinicalTrials.gov