Dietary Interventions During Living Kidney Donations
ConditionLiving-Kidney Donors
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Cologne
About this trial
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney biopsy samples in patients preconditioned by different dietary regimes (fasting mimicking diet vs. ketogenic diet vs. dietary restriction of sulfur containing amino acids vs. control patients)
Eligibility criteria
Qualifiers
Patients > 18 years of age
Planed living kidney transplantation (both donor and recipient are eligible)
Written informed consent
Disqualifiers
Vegetarian lifestyle
Body-Mass-Index (BMI) < 18.5 kg/m2
Calorie-reduced diet within the preceding four weeks
Underlying wasting syndrome
Trial design
Treatments tested in this trial
- Fasting mimicking diet
- Ketogenic diet
- Dietary restriction of sulfur containing amino acids
- Control Group ( healthy, low-fat, moderate protein and high carbohydrate diet)
Treatment groups
80 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov