Dietary Modification In Inflammatory Bowel Disease Patients

ConditionCrohn Disease
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity of Malaya

About this trial

This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED). The study will be conducted in inflammatory bowel disease patients in University Malaya Medical Centre, which are ulcerative colitis and Crohn's disease patients. The objectives of this study are to assess the impact of diet in clinical outcome and gut microbiota changes in patients with inflammatory bowel disease (IBD). The study duration spans 24 weeks, during which comprehensive follow-ups will be conducted at 0, 6, 12, and 24 weeks, respectively. At each follow-up session, participants will be requested to provide stool and blood samples for meticulous assessment of clinical and biochemical responses.

Eligibility criteria

Qualifiers

Confirmed diagnosis of Crohn's disease according to established clinical, endoscopic, and histological criteria.

Mild to moderate diseases (150 to 220 points).

Written informed consent obtained.

Disqualifiers

Presence of stoma.

Surgery within 6 months prior to randomization.

Patient on exclusive enteral nutrition (EEN).

Trial design

Treatments tested in this trial

  • General Healthy Diet
  • Crohn's Disease Exclusion Diet (CDED)

Treatment groups

74 Participants
are divided into 2 treatment groups

Sponsors and collaborators