Dietary Potassium Liberalization in Pre-Dialysis Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Manitoba
About this trial
The study will look at the impact of the potassium content in fruits and vegetables, on serum potassium concentrations in people with Chronic Kidney Disease (CKD) using a randomized crossover design. Participants will receive home delivery of fruit and vegetables with either higher or lower potassium content in a random order. Clinical chemistry markers from blood and urine samples, blood pressure, physical functioning and health related quality of life will be assessed throughout the duration of the trial. This study will also measure their physical functioning, using a chair stand test. The results of this study could change the dietary recommendations for people with CKD related to potassium.
Eligibility criteria
Qualifiers
Male or female, aged 18 years or above
Participants who have an estimated glomerular filtration rate between 15 and 45 ml/min/1.73m2
Serum potassium concentration between 4.5 and 5.5 milliequivalent (mEq)/L
Hemoglobin A1c ≤ 11%
Disqualifiers
Serum potassium concentration > 5.6 mEq/L, anuria, dialysis, or acute kidney injury failure in the 6 months prior to screening
Chronic obstructive pulmonary disease that requires the participant to be on oxygen
New York Heart Association Class 3-4 Heart symptoms or heart, liver or renal transplant
A myocardial infarction or stroke within the last 6 months
Trial design
Treatments tested in this trial
- Liberalized dietary potassium via fruits and vegetables
- Standard dietary potassium restriction
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Manitoba
Lead sponsor
Dalhousie University
Collaborator
Source ClinicalTrials.gov