Dietary Tracking in Heart Failure

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe Cleveland Clinic

About this trial

Emerging evidence links ultra processed foods (UPFs) to adverse cardiovascular outcomes. UPFs are often high in sodium, unhealthy fats and added sugars, while being low in essential nutrients and fiber. UPFs contribute to systemic inflammation, fluid retention, and metabolic dysfunction-key drivers of HF and kidney disease progression. Traditional dietary counseling often lacks specificity around food processing levels. Furthermore, the majority of nutrition studies relied on extensive self-reported dietary recall food frequency questionnaires (FFQ) that are subjective, often labor intensive, and difficult to implement practically in the clinical setting. As such, researchers have developed metabolite scores from blood and urine samples to help quantify UPF consumption, which has the promise to better guide dietary counseling and track process. Therefore, the aim of this study is to evaluate the feasibility and physiological impact of a structured UPF-reduction dietary intervention in patients with HF, leveraging both digital dietary tools (Cronometer) and biomarker assessments.

Eligibility criteria

Qualifiers

Adults (≥18 years) with NYHA Class II-III HF

Able to use Cronometer to track dietary intake and able to prepare food at home independently (able to modify dietary intake)

Disqualifiers

History of heart transplant or LVAD implant

Unable or unwilling to follow dietary coaching for UPF reduction

eGFR <30 ml/kg/1.73m2

Trial design

Treatments tested in this trial

  • Limiting Ultraprocessed Food (UPF) in Diet

Treatment groups

No treatment groups listed

Sponsors and collaborators