The goal of this observational study is to learn about remote mental health monitoring technology for adults with treatment-resistant depression. The main question it aims to answer is: are digital mental health monitoring tools (an electronic data capture platform and wearable device (e.g., smartwatch or smart-ring)) feasible to implement alongside clinical treatment for depression? The secondary aim of this study is to inform preliminary clinical parameters for larger, definitive studies.
Participants receiving neuropsychiatric treatment (repetitive transcranial magnetic stimulation, intravenous ketamine, or electroconvulsive therapy) as part of their regular medical care for treatment-resistant depression in the Interventional Psychiatry Program will have their clinical assessment data entered into a digital platform and will wear an accessory-based wearable device for the duration of treatment.
Adults (aged 18+) who are capable of giving informed consent
Patients meeting diagnostic criteria for major depressive disorder (MDD) without psychotic symptoms according to the DSM-5
Currently experiencing a major depressive episode (MDE)
Montgomery-Asperg Depression Rating Scale (MADRS) score greater than 20 at screening
Individuals without Internet access (required to access study platforms)
Medication changes, aside from the treatment received through the IPP, one month (28 days) before screening, or during the entire duration of treatment (variable based on treatment arm)
Participants who do not speak English fluently enough to successfully communicate study information, answer questions accurately, and/or obtain informed consent
Unity Health Toronto
Lead sponsor
University of Toronto
Collaborator
Toronto Metropolitan University
Collaborator