Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorMilitary Hospital 103
About this trial
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis. Eighty participants will be allocated to two parallel groups: scaling and root planing (SRP) with adjunctive diode laser therapy or SRP alone. Clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles will be assessed at baseline and during follow-up. The study aims to determine whether adjunctive diode laser therapy provides superior clinical and biological improvement compared with SRP alone.
Eligibility criteria
Qualifiers
Kidney transplant recipients aged 18 years or older.
Diagnosis of periodontitis according to the study case definition.
Medically stable and able to undergo non-surgical periodontal treatment.
Willing and able to provide written informed consent and attend follow-up visits.
Disqualifiers
- Periodontal treatment or systemic antibiotic use within the predefined exclusion window in the protocol.
Acute oral infection requiring urgent treatment.
Pregnancy or lactation, if excluded by the approved protocol.
Serious systemic condition or clinical instability judged by investigators to preclude study participation.
Trial design
Treatments tested in this trial
- Scaling and Root Planing
- Diode Laser
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov