Direct Warming Frozen Embryo Transfer Outcomes in Assisted Reproductive Technology

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorChinese University of Hong Kong

About this trial

The goal of this clinical trial is to evaluate whether the direct warming method for frozen embryo transfers (FET) can improve live birth and pregnancy outcomes in women aged 18-45 undergoing IVF treatments. The main questions it aims to answer are:

* Does the direct warming method achieve a similar or higher clinical success rate for FET compared to the conventional multi-step method? * Is the direct warming method more cost-effective than the conventional method?

Researchers will compare the direct warming method to the conventional multi-step method to see if the former leads to better pregnancy outcomes and reduced procedural time.

Participants will:

* Undergo either the one-step or conventional embryo thawing procedure. * Complete standard clinical follow-ups for pregnancy, including ultrasound scans and pregnancy tests.

Eligibility criteria

Qualifiers

Plan to undergo single embryo transfer (SET) during the FET cycle.

Age between 18 and 45 years.

Patients with at least one high-quality blastocyst available for transfer.

Patients who have provided informed consent to participate in the study.

Disqualifiers

Patients with repeated implantation failure (RIF) or recurrent miscarriage (RM).

Patients with known uterine anomalies or significant uterine pathology (e.g., fibroids, polyps).

Patients who are unwilling or unable to provide informed consent.

Trial design

Treatments tested in this trial

  • Direct Warming Method
  • Conventional Multi-step Thawing Method

Treatment groups

578 Participants
are divided into 2 treatment groups