Discovery of Biomarkers for Intrinsic Radiation Sensitivity in Cancer Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21-99
SponsorNational Cancer Centre, Singapore

About this trial

Patients with cancers that are sensitive to radiotherapy treatment and/or patients who have experienced severe acute/ late side effects to radiotherapy will be recruited to the study. Blood and/or matched tumour-normal tissue pairs will be collected. Blood and/or tissue samples will be processed and studied for genetic and biochemical markers that have potential to be used for predicting sensitivity to radiation.

Eligibility criteria

Qualifiers

Patients with severe side effects from radiotherapy

Patients with a type of cancer that is associated with sensitivity to radiotherapy

Disqualifiers

Age of patient must be between 21 (inclusive) and 99 (exclusive)

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators

National Cancer Centre, Singapore

Lead sponsor

National Medical Research Council (NMRC), Singapore

Collaborator

Duke-NUS Graduate Medical School

Collaborator

Ferring Pharmaceuticals

Collaborator

ImmunoSCAPE

Collaborator

Decipher Biosciences

Collaborator