DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age8-15
SponsorGeorge Washington University
About this trial
The goal of the DISCOVERY study is to provide innovative critical information regarding the unique natural history of glycemic control, insulin sensitivity, and β-cell function, and their mechanistic determinates, in obese adolescents at risk for developing type 2 diabetes.
Eligibility criteria
Qualifiers
Overweight or obesity with BMI ≥85th percentile
Age 8-13 year for girls, 9-15 year for boys (inclusion younger for girls as puberty tends to start a year earlier in girls)
Tanner Stage 2, 3, or 4
Elevated HbA1c 5.5-6.4%
Disqualifiers
Diabetes based on history, or HbA1c ≥6.5% in the medical record or at screening
Unable/unwilling to provide consent/participate fully
Conditions predisposing to diabetes or altering the trajectory of puberty
Medications affecting glucose dynamics during the screening and enrollment period
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov