About this trial
Controversy remains around the role of ultra-processed food (UPF) consumption and health outcomes. A key question that remains to be answered is: when diet quality is the same, does food processing itself have any independent health effects? The current application aims to isolate the health effects of food processing from those of diet quality through the conduct of a dietary intervention study.
Eligibility criteria
Qualifiers
Men and women aged between 18 and 65 years in general good health with BMI < 35 kg/m2 who can provide informed consent.
Disqualifiers
Participants will be ineligible to enrol if they have diabetes, CVD, any type of cancer (except for basal cell skin cancer), or a condition (pregnancy, breastfeeding, etc) or dietary restriction(s) that would substantially limit their ability to complete the study.
Individuals with low adherence will enter run-in phase only (6 weeks)
Individuals with high adherence will enter the main intervention (4 months)
Trial design
Treatments tested in this trial
- High UPF, high hPDI diet
- Low UPF, high hPDI diet
Treatment groups
Sponsors and collaborators
Queen's University, Belfast
Lead sponsor
University College Dublin
Collaborator
Harvard School of Public Health (HSPH)
Collaborator