About this trial
This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as well as more traditional intoxication measures such as breath alcohol concentration and balance metrics. If eligible for the study, participants will be randomized to complete one study session in our mobile laboratory, during which they will use either alcohol, cannabis (which will be self-administered, ad libitum) or both alcohol and cannabis.
Eligibility criteria
Qualifiers
21-50 years old
Heavy drinkers (consuming more than 4 drinks/day or more than 14 drinks/week for men, or more than 3 drinks/day or more than 7 drinks/week for women)
Regular users of legal-market flower cannabis (at least 2x/week in past 3 months)
report simultaneously using alcohol and legal-market flower cannabis at least once per month in the past 3 months
Disqualifiers
Daily tobacco users
Diagnosed with or seeking treatment for alcohol use disorder (AUD) or other substance use disorder (SUD)
Females cannot be pregnant, breastfeeding or trying to become pregnant
Meet criteria for psychotic, bipolar or major depressive disorder with suicidal ideation, or history of these disorders, 5) Current use of psychotropic (except anti-depressants)
Trial design
Treatments tested in this trial
- Alcohol
- Cannabis