DNA Repair Activity in the Skin of Day and Night Shift Workers

ConditionSkin Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorWright State University

About this trial

The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.

Eligibility criteria

Qualifiers

Male/Female

Fair skin (Fitzpatrick types I and II)

Age 18 to 40

Able to comprehend procedures/risks

Disqualifiers

Known photosensitivity

Currently on photosensitizing medications

Diabetes Mellitus

On any hormonal agents (e.g., birth control pills)

Trial design

Treatments tested in this trial

  • Ultraviolet B Radiation
  • No Ultraviolet B Radiation

Treatment groups

48 Participants
are divided into 2 treatment groups

Sponsors and collaborators