Does Hyaluronic Acid Help Relieve Dry Mouth?
ConditionXerostomia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Barcelona
About this trial
The goal of this clinical trial is to learn if hyaluronic acid infiltration helps relieve dry mouth symptoms in adults with xerostomia. It will also assess the safety and duration of the treatment's effects.
The main questions it aims to answer are:
1. Does hyaluronic acid improve the sensation of dry mouth? 2. What side effects may occur after treatment? 3. How long does the effect of the treatment last? 4. Are there changes in salivary flow and pH after treatment?
Researchers will compare hyaluronic acid to a placebo (a look-alike substance with no active ingredient) to determine its effectiveness.
Participants will:
Receive submucosal injection of either hyaluronic acid or placebo Visit the clinic once a month for 6 months for follow-up evaluations Not be required to perform any tasks at home
Eligibility criteria
Qualifiers
Patients over 18 years of age
Patients reporting symptoms compatible with xerostomia for at least one year
Patients who agree to cooperate in the study, comply with the follow-up plan, and sign the informed consent
Disqualifiers
Underage patients
Pregnant patients
Patients on antiplatelet or anticoagulant therapy
Patients with a history of adverse reactions to hyaluronic acid infiltration
Trial design
Treatments tested in this trial
- Submucosal infiltration of non reticulated hyaluronic acid
- Submucosal infiltration of Placebo
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov