Dosing and Deployment Trial: A Home-based Optokinetic Treatment

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-110
SponsorDuke University

About this trial

Several interventions exist for remediation of spatial neglect, but they have mixed evidence. Optokinetic stimulation is a bottom-up intervention; in other words, it is a stimulus-driven process, with Level A (strongest) evidence, and is recommended in clinical practice guidelines such as the American Heart Association's stroke guidelines. The studies currently published all use varing doses (number of sessions a week), did not assess the impact on mobility and risk of falls, and have not been implemented in the home setting. It is imperative to understand how to successfully implement this intervention at home, and learn how it will impact mobility in order to better support a large population of individuals living with chronic spatial neglect and who face barriers to accessing care because they require caregiver support to leave the home. This will be done using both qualitative and quantitative methods.

Eligibility criteria

Qualifiers

first and unilateral right brain damage stroke, confirmed by medical records,

time post stroke >6 months,

moderate to severe SN, classified using the Catherine Bergego Scale (CBS) via the Kessler Foundation Neglect Assessment Process (KF-NAP),

over age of 60 years, and

Disqualifiers

history of multiple strokes or neurological incidents (e.g., traumatic brain injury, seizures, or brain tumor),

unable to communicate through spoken English, screened using the Aphasia Rapid Test (ART), as instructions for treatment and assessment tasks will be provided verbally in English,

cognitive impairment as defined by the Blind-MoCA,

dependent in mobility- walking or wheelchair via medial chart,

Trial design

Treatments tested in this trial

  • Optokinetic stimulation

Treatment groups

90 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators