Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIstanbul Mehmet Akif Ersoy Educational and Training Hospital

About this trial

The Crush technique for coronary bifurcation lesions has evolved significantly since its introduction to the literature by Colombo et al. in 2003, with several iterations, including double kissing balloon inflation. The main disadvantage of the historical Crush technique is the low success rate of the final kissing balloon inflation. An improvement came with the introduction of double kissing crush stenting aiming for the shorter protrusion and kissing balloon dilation performed before and after main branch stent implantation. The double kissing crush provides a significant reduction in major adverse cardiovascular events compared to Provisional stenting, Crush, and Culotte techniques. Recently, a novel modified mini-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired, and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon), and this causes less disruption of the stent cells. To date, no data compares the mid-term outcomes of double kissing crush and controlled balloon-crush stenting techniques in patients with complex coronary bifurcation lesions. Hence, this study aimed to determine the clinical results of double kissing crush and controlled balloon-crush techniques under mid-term follow-up.

Eligibility criteria

Qualifiers

Aged >18

PCI with either DK-crush or Controlled balloon-crush

Complex coronary bifurcation lesion (Medina 0.1.1, Medina 1.1.1)

Disqualifiers

Non-complex bifurcation anatomy

Bail-out 2-stent (reverse modified mini-crush)

ST-elevation myocardial infarction

Cardiogenic shock status

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

300 Participants
are grouped into 2 trial groups

Sponsors and collaborators

Istanbul Mehmet Akif Ersoy Educational and Training Hospital

Lead sponsor

Sisli Hamidiye Etfal Training and Research Hospital

Collaborator

Başakşehir Çam & Sakura City Hospital

Collaborator

Bagcilar Training and Research Hospital

Collaborator

Ankara Etlik City Hospital

Collaborator

Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital

Collaborator

Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital

Collaborator

Istanbul Medipol University Hospital

Collaborator