DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40+
SponsorKing's College Hospital NHS Trust

About this trial

This is a feasibility study to assess new, more practical ways of measuring renal reserve.

Eligibility criteria

Qualifiers

Patients with sickle cell nephropathy, diagnosed clinically or histologically. Sickle Cell patients will be confirmed Hb SS and eGFR (CKD-EPI) ≥ 135 ml/min/1.73m2 OR

Previous living kidney donation

Age ≥ 4No contraindication or known allergy to any trial medications.

Willing and able to provide written informed consent

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Dapagliflozin

Treatment groups

44 Participants
are divided into 2 treatment groups

Sponsors and collaborators

King's College Hospital NHS Trust

Lead sponsor

King's College London

Collaborator