About this trial
The goal of this observational study is to investigate how bacterial populations from the intestine and mouth of patients change during the hospitalization period and evaluate if some populations of specific bacteria increase or decrease the risk of acquiring an infection or becoming colonized by pathogenic bacteria. Participants will have the following samples collected during enrollment: stool samples (maximum 2x/week), blood draws (1x/week), oral swab (1x/week).
Eligibility criteria
Qualifiers
Admission to an intensive care unit or stem cell transplant unit (for allogeneic stem cell transplantation) within previous 24 hours
Disqualifiers
<18 years of age
Pregnancy
History of inflammatory bowel disease (Crohn's disease, ulcerative colitis)
Gastrointestinal derivation (colostomy, ileostomy, etc.)
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
The Methodist Hospital Research Institute
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator
M.D. Anderson Cancer Center
Collaborator
Baylor College of Medicine
Collaborator
University of Houston
Collaborator
William Marsh Rice University
Collaborator
The University of Texas Health Science Center, Houston
Collaborator