Early Ageing During Therapy in AYA Cancer Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-39
SponsorUniversity Medical Center Groningen

About this trial

Longitudinal cohort study; measurements before start of systemic therapy and one year later.

Eligibility criteria

Qualifiers

Aged 18-39 years at cancer diagnosis

Having a histologically and/or cytologically confirmed cancer diagnosis, including leukemia, (non-)Hodgkin lymphoma, testicular cancer, osteosarcoma, Ewing sarcoma, breast cancer, and cervical cancer.

Scheduled to start systemic therapy with curative intent. Allowed treatments (concurrent or sequential) are: surgery, radiotherapy, chemotherapy, antibodies.

Disqualifiers

patients who are not able to understand the patient information letter and informed consent form

patients who will be treated with immune checkpoint inhibitors or targeted therapy with inhibitors of angiogenesis

patients who have been treated with systemic therapy or radiotherapy for a previous malignancy (exceptions: in situ carcinoma of the cervix or uterus and adequately treated basal and squamous cell carcinoma of the skin).

Trial design

Treatments tested in this trial

  • Blood sampling

Treatment groups

120 Participants
are divided into 1 treatment group

Sponsors and collaborators

University Medical Center Groningen

Lead sponsor

UMCG Kanker Researchfonds

Collaborator