Early Detection of At-risk Septic Patients

ConditionSepsis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Southampton NHS Foundation Trust

About this trial

The purpose of this study is to determine whether additional investigations used in other parts of healthcare can be used in the Emergency Department to identify critically ill patients quicker than usual care.

Eligibility criteria

Qualifiers

Differential diagnosis which includes infection

Change in the quick Sequential Organ Failure Assessment (qSOFA) ≥2 or National Early Warning Score 2 (NEWS2) score ≥5

Aged ≥18 years

Disqualifiers

Traumatic injury

Rockwood frailty score ≥6

Critical care therapy previously believed to not be in patient's best interests

Advanced directive refusing critical care therapies.

Trial design

Treatments tested in this trial

  • Measuring tissue oxygenation
  • Procalcitonin
  • Mid-regional proadrenomedullin
  • Hand-held video microscope

Treatment groups

60 Participants
are divided into 1 treatment group