About this trial
This trial is a prospective, exploratory and descriptive study. The primary objective is to identify early diagnostic biomarkers in patients with TIPMP based on the analysis of Treg lymphocyte subpopulations and epigenetic signatures, and the secondary objective is to characterize the biological processes underlying the transformation of a pre-neoplastic lesion into established ADPC.
Eligibility criteria
Qualifiers
Age over 18
Patient with intermediate-risk or high-risk TIPMP according to the European Study Group on Cystic Tumours of the Pancreas (3)
Signed consent to participate
Affiliation with a social security scheme, or beneficiary of such a scheme.
Disqualifiers
Pregnant or breast-feeding woman
Person in an emergency situation or unable to give consent.
Adult subject to a legal protection measure (adult under guardianship, curatorship or safeguard of justice),
Unable to undergo medical follow-up for geographical, social or psychological reasons.
Trial design
Treatments tested in this trial
- blood sampling at inclusion, 6 months, 1 year and 2 years. Tumor and intracystic fluid samples are taken only if a biopsy is planned following MRI results.