Early Neurodivergent Developmental Trajectories in Autism and in Response to the ESDM Intervention

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-36
SponsorIstituto per la Ricerca e l'Innovazione Biomedica

About this trial

Early support is thought to be key to ensure a better quality of life for young children on the autism spectrum. Among early support, different evidence-based approaches have combined the principles of developmental and behavioral science within a naturalistic and interactive frame and grouped under the umbrella of Naturalistic Developmental Behavioral Interventions (NDBI). In the context of NDBIs, the Early Start Denver Model is a manualized support that has reported evidence of efficacy for therapist-, group- and caregiver-implemented support, in multiple research as well as community based settings, different countries and languages (Rogers \& Dawson, 2010). Understanding the effects of support characteristics and intensity on individual learning has a major impact on the delivery systems organization and policies, sustainability in low resources community settings and to provide the necessary support to the family. However, a direct comparison among different types and intensity of early support in community setting and relatively low access to standardized and intensive programs, have not been adequately explored. For this reason, the aim of this study is to investigate, in a community setting in the Italian context, the impact of ESDM and support intensity on individual developmental trajectories.

Eligibility criteria

Qualifiers

unimpaired hand use

parent agreement to have a caregiver present during all home sessions

attendance at all intake sessions

permission to videotape evaluations and ESDM treatment

Disqualifiers

serious parental substance abuse

parental self-report of bipolar disorder or psychosis

known genetic syndromes

serious medical conditions (e.g., encephalitis, concussion, seizure disorder)

Trial design

Treatments tested in this trial

  • Early Start Denver Model (ESDM)

Treatment groups

33 Participants
are divided into 1 treatment group

Sponsors and collaborators

Istituto per la Ricerca e l'Innovazione Biomedica

Lead sponsor

Istituto Superiore di Sanità

Collaborator

Messina, Italy

Collaborator

Società Cooperativa Sociale AUDACIA

Collaborator

Associazione Ulisse

Collaborator

La Linea Curva

Collaborator