Early Neurophysiological Markers of Language Impairments

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-8
SponsorIRCCS Eugenio Medea

About this trial

The present project aims at identifying very early electrophysiological risk markers for language impairments. The long-term goals of the study include the characterization of learning developmental trajectories in children at high risk for language impairments. In this project, all the infants of the Medea BabyLab cohort are followed-up until school age. Since these infants have complete information on early electrophysiological markers, the final goal of the project is the characterization of their learning developmental trajectories and the construction of a multi-factor prognostic model that includes the neurophysiological processes underlying basic-level skills as potential biomarkers for predicting later reading and spelling skills.

Eligibility criteria

Qualifiers

Healthy infants aged <24 months

Infants with and without familial risk for language impairments (infants are assigned to the group with familial risk if at least one first-degree relative had a certified (clinical) diagnosis of language impairment or learning disability

Both parents are native-Italian speakers

Disqualifiers

Gestational age < 37 weeks and/or birth weight < 2500 grams

APGAR scores at birth at 1' and 5' < 7

Bayley Cognitive Score < 7

Presence of certified diagnosis of intellectual deficiency, attention-deficit disorder, sensorial and neurological disorders, or autism within first-degree relative

Trial design

Treatments tested in this trial

  • Electrophysiological recording
  • Behavioral assessment

Treatment groups

100 Participants
are divided into 1 treatment group

Sponsors and collaborators