About this trial
The purpose of this study is to evaluate if it is possible to use intravaginal high-density surface electromyography to guide Botulinum neurotoxin (BoNT) injection to treat pelvic floor muscle overactivity that complicates Chronic Pelvic Pain (CPP).
Eligibility criteria
Qualifiers
Woman aged 18 to 60.
Have a clinical diagnosis of IC/BPS.
Pain, pressure, or discomfort in the bladder and/or pelvic area for the past 6 months or more, associated with lower urinary tract symptoms (such as frequency of urination), in the absence of other explanation of the symptoms (e.g., urinary tract infection).
Myofascial pain diagnosed with palpable contracted muscle fibers.
Disqualifiers
History of pelvic malignancy and sexually transmitted diseases.
Bleeding disorder such as coagulopathy
History of neurological disorders, such as spinal cord injury, multiple sclerosis, amyotrophic lateral sclerosis or myasthenia gravis.
Pregnancy, breast feeding or desiring for pregnancy in the coming year.
Trial design
Treatments tested in this trial
- High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device
- Botulinum Neurotoxin