The goal of this clinical trial is to investigate the abundance of a natural odour in human cerebrospinal fluid in obese and lean participants after inhalation thereof. Participants will undergo blood sample collection and inhalation of either a natural odour or placebo through an inhaler in addition to a liquor puncture prescribed in standard of care context.
Age 18-60 years
Written informed consent
Scheduled for routine liquor puncture
BMI ≥ 30 kg/m2
Known allergy to the natural odour
Acute upper respiratory tract infection, acute or chronic sinusitis
Present or past surgical intervention of the nasal cavity, the paranasal sinus, the pituitary or the frontal brain
Pregnancy/lactation