This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated caries-affected dentin and the influence of Er, Cr: YSGG Laser treatment.
o Patients aged (20 - 40) years.
Presence of at least one posterior permanent molar with an occlusal carious lesion classified as ICDAS code 3 or 4 requiring operative treatment.
Good general and oral health.
Willingness to participate and provide informed consent.
o Patients with systemic conditions affecting oral health or healing.
Teeth with pulp involvement or periapical pathology.
Allergy to study materials.
Poor oral hygiene or periodontal disease in the target tooth region.
Al-Azhar University
Lead sponsor
Misr University for Science and Technology
Sponsor institution