Cocaine and Pentoxifylline (BED IN 47)
ConditionCocaine Use Disorder
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-55
SponsorWilliam Stoops
About this trial
This will be a human laboratory study evaluating the influence of pentoxifylline treatment on the effects of cocaine. Supported by and included in the Helping to End Addiction Long-term® (HEAL) Initiative.
Eligibility criteria
Qualifiers
able to speak/read English,
not seeking treatment for drug use at the time of the study,
female or male between the ages of 18 and 55 years,
recent smoked or intravenous cocaine use verified by benzoylecgonine positive urine, as well as fulfillment of DSM-5 diagnostic criteria for CUD,
Disqualifiers
unable to speak/read English,
seeking treatment for drug use,
under 18 years or over 55 years,
no recent smoked or intravenous cocaine use as indicated by benzoylecgonine negative urine and no DSM-5 diagnosis of CUD,
Trial design
Treatments tested in this trial
- Placebo
- Cocaine (IV)
- Pentoxifylline
Treatment groups
30 Participants
are divided into 3 treatment groupsSponsors and collaborators
William Stoops
Lead sponsor
University of Kentucky
Sponsor institution
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov