Combined Blood Pressure Medication and Activity Scheduling for Low Mood

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Oxford

About this trial

This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood

Eligibility criteria

Qualifiers

Willing and able to provide informed consent

Aged 18-65 years

Self-reported low levels of positive mood

Sufficient written and spoken English skills to understand study procedures

Disqualifiers

Antidepressant treatment or medication in last three months

Currently receiving cognitive-behavioural therapy with behavioural activation

History of psychosis or bipolar disorder

History of substance dependence

Trial design

Treatments tested in this trial

  • Losartan with BA
  • Placebo with BA

Treatment groups

76 Participants
are divided into 2 treatment groups

Sponsors and collaborators