Combined Blood Pressure Medication and Activity Scheduling for Low Mood
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Oxford
This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood
Willing and able to provide informed consent
Aged 18-65 years
Self-reported low levels of positive mood
Sufficient written and spoken English skills to understand study procedures
Antidepressant treatment or medication in last three months
Currently receiving cognitive-behavioural therapy with behavioural activation
History of psychosis or bipolar disorder
History of substance dependence