Differing Levels of Hypoglycemia
ConditionHypoglycemia
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-55
SponsorUniversity of Maryland, Baltimore
About this trial
Hypoglycemia can produce a spectrum of pro-inflammatory and pro-atherothrombotic changes. To date no studies appear to have investigated the effects of differing levels of hypoglycemia on the vasculature and pro-atherothrombotic balance during hypoglycemia in healthy man. The specific aim of our study will be to determine the effects of differing levels of hypoglycemia on in-vivo vascular biologic mechanisms in a healthy population.
Eligibility criteria
Qualifiers
None
Disqualifiers
Pregnant women
Subjects unwilling or unable to comply with approved contraception measures
Subjects unable to give voluntary informed consent
Subjects on anticoagulant drugs, anemic or with known bleeding diatheses
Trial design
Treatments tested in this trial
- Glucose clamp
Treatment groups
32 Participants
are divided into 4 treatment groupsSponsors and collaborators
University of Maryland, Baltimore
Lead sponsor
Vanderbilt University
Collaborator
Source ClinicalTrials.gov