To compare the effect of Bio-C Temp Bioceramic intracanal dressing versus calcium hydroxide as intracanal medicaments on:
* Intensity of postoperative pain * levels of MMP -9 in Periapical Fluids.
Age between 18-50 years old.
Males and females.
Healthy patients categorized as I or II according to The American Society of Anesthesiologists.
Diagnosed clinically with pulp necrosis.
Medically compromised patients having significant systemic disorders (ASA III or IV).
Pregnant females.
If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively as it might alter their pain perception.
Teeth with multiple canals. 9