Evaluation of the Electronic Cigarette Withdrawal Syndrome
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age21-55
SponsorJohns Hopkins University
About this trial
The goal of this project is to rigorously evaluate the nature of e-cigarette withdrawal in exclusive e-cigarette users during a monitored abstinence period and the role of nicotine in the expression of this withdrawal syndrome.
Eligibility criteria
Qualifiers
21-55 years old
good general health as reviewed by study medical team
vital signs in normal range as reviewed by study medical team
negative urine test for illicit drug use (excluding THC) and negative breath alcohol test
Disqualifiers
psychoactive drug use (aside from cannabis, nicotine, alcohol, caffeine) in past month
current use of over-the-counter (OTC) or prescription medications that may impact safety
use cannabis >2 times per week
history of or current significant medical condition that would impact participation or safety according to the study investigators and medical staff
Trial design
Treatments tested in this trial
- Transdermal Nicotine Patch
- Placebo Nicotine Patch
Treatment groups
150 Participants
are divided into 3 treatment groupsSponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov