About this trial
\[68Ga\]Ga-PentixaFor PET-CT will be performed in patients with Small cell lung cancer (SCLC) to confirm the targeting of CXCR4 by \[68Ga\]Ga-PentixaFor
Eligibility criteria
Qualifiers
Written informed consent signed before performing any trial specific procedure.
Male or female, age ≥ 18 years at time of study entry.
Patient with histologically proven small cell lung carcinoma, inoperable, non-pre-treated.
Metastatic disease documented by conventional imaging and/or [18F]FDG PET-CT with at least one metastatic measurable lesion (RECIST 1.1). Patients eligible for 1st line metastatic treatment.
Disqualifiers
History of cancer in the 3 years prior to entry into the trial other than basal cell carcinoma of the skin or carcinoma in situ of the cervix.
History of anti-cancer treatments such as chemotherapy, radiotherapy or immunotherapy as well as other clinical trials for SCLC before the first [68Ga]Ga-PentixaFor PET-CT imaging.
Inability to lie still for at least 1 hour, or known claustrophobia.
Serious non-malignant disease (e.g., psychiatric, infectious, autoimmune, or metabolic) which may interfere with study objectives or patient safety or compliance, in the judgment of the investigator.
Trial design
Treatments tested in this trial
- [68Ga]Ga-PentixaFor