Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age65+
SponsorWeinberg Medical Physics LLC

About this trial

The goal of this study is to learn if manipulating the brain using magnets works to treat balance impairment, a major cause of falls, in older adults with balance problems. The technique to manipulate the brain using magnets is known as transcranial magnetic stimulation or TMS.

The main questions this study aims to answer are:

* How does TMS change communication between brain areas? * Does TMS improve balance ability in older adults with balance problems? Researchers will compare the TMS group to a placebo group to see if manipulating the brain using magnets works to treat balance impairment.

Participants will:

* Receive TMS or placebo stimulation for 4 weeks. * Visit the laboratory for checkups and tests 3 times.

Eligibility criteria

Qualifiers

None

Disqualifiers

Inability to provide informed consent.

Non-English speaking.

Have contraindications to TMS based on TMS Adult Safety Screen (e.g., pregnancy, metal in the brain/skull, neurostimulator, pacemaker, infusion device, medication to treat mental illness)

Unintentional weight loss of ≥10 pounds over the past year.

Trial design

Treatments tested in this trial

  • Transcranial Magnetic Stimulation
  • Transcranial Magnetic Stimulation Sham

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Weinberg Medical Physics LLC

Lead sponsor

University of Houston

Collaborator

National Institute on Aging (NIA)

Collaborator