This is a single arm feasibility study of exercise for improving long- course neoadjuvant chemoradiotherapy (NACRT) efficacy in people diagnosed with locally advanced rectal cancer. The study aims to recruit up to 30 patients from the Queen's Centre for Oncology and Haematology of Castle Hill Hospital, Cottingham, diagnosed with locally advanced rectal cancer. Consenting patients will be provided with an 11-week course of structured aerobic exercises and resistance training in the periods before, during and after their chemoradiotherapy treatment. The patients will be followed up for 6 months post long course neoadjuvant chemoradiotherapy (NACRT), with a total of 3 assessment periods.
18 years or older
Have been diagnosed with locally advanced rectal cancer using MRI (Magnetic Resonance Imaging) and histological finding
Have been offered long-course neoadjuvant chemoradiotherapy in the Queens Centre, Castle Hill Hospital
Willing and able to comply with all study requirements
Inability to understand basic written and spoken English, as research materials will all be written in English.
Any movement deficiencies limiting ability to engage in exercise.
Impaired cognition and/or capacity limiting ability to provide informed consent.
Cardiovascular and/or cardiopulmonary conditions that will impede ability to safely perform exercise.
University of Hull
Lead sponsor
Hull University Teaching Hospitals NHS Trust
Collaborator