This early phase I is to find out how common vitamin D insufficiency is among African American patients with a history of prostate cancer that has not spread to other parts of the body (localized) or has spread to other places in the body (metastatic) and how vitamin D insufficiency affects the immune system. This study also aims to find out if replacing vitamin D results in normalization of the immune function. Information from this study may benefit prostate cancer patients by identifying vitamin D insufficiency which in several studies had been found to contribute to more aggressive prostate cancers.
African American males, age >= 18 years
Patients with a previous history of localized or metastatic or locally recurrent prostate cancer
Patients with Vitamin D levels below 30 ng/ml
Known hypersensitivity to vitamin D
End stage renal failure on dialysis
Liver cirrhosis
Currently taking a vitamin D or multivitamin supplement, that has more than 400 IU/10mcg of vitamin D daily for the past month
Mayo Clinic
Lead sponsor
Congressionally Directed Medical Research Programs
Collaborator