Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexFemale
Age18-70
SponsorUniversity of Missouri-Columbia

About this trial

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

Eligibility criteria

Qualifiers

Female assigned at birth

Pre, peri- or post-menopausal

Healthy weight (BMI ≥18 and ≤30 kg/m2)

Disqualifiers

Male (assigned at birth)

Pregnancy, breastfeeding

Use of hormone replacement therapies

Hysterectomy

Trial design

Treatments tested in this trial

  • Placebo
  • Propranolol
  • Gemtesa

Treatment groups

75 Participants
are divided into 3 treatment groups