Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNorthwell Health

About this trial

By tracking resting-state fMRI scans, we aim to discover how repetitive transcranial magnetic stimulation (rTMS) changes brain connectivity in individuals with dystonia.

Eligibility criteria

Qualifiers

Male or female

18 and 80 years of age.

Patients who manifest dystonia - sustained involuntary movement of the head, neck, trunk or limbs.

The dystonia may be spontaneous or genetic, specifically DYT1 or DYT6 and then only those patients who are demonstrating dystonia. The patient/subject will have a normal neurological exam except for dystonia.

Disqualifiers

Heredodegenrative dystonia of the type DYT8,9 or 10.

Past history of head trauma, stroke, epilepsy, demyelinating disease

Hypertension in excess of 160mmHg systolic and 90mmHg diastolic

Congestive heart failure

Trial design

Treatments tested in this trial

  • Transcranial Magnetic Stimulation

Treatment groups

10 Participants
are divided into 1 treatment group

Sponsors and collaborators