JIT: Effect of Pain on DT in TMD
ConditionTemporomandibular Disorder (TMD)
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age21-65
SponsorUniversity of Minnesota
About this trial
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.
Eligibility criteria
Qualifiers
Participants in this study must be 21 years to 65 years of age and provide a driver's license or other state-issued ID.
Participants must also be sufficiently fluent in English to provide informed consent and understand questionnaires and instructions for laboratory procedures.
Participants must report drinking of, on average, at least 1 drink 3 days/week over the past 6 months.
Meet Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for myalgia (masticatory muscle pain), arthralgia (TMJ pain), or a combination (Schiffman et al., 2014) (TMD group only).
Disqualifiers
Use of opioid analgesics within the past month;
Current major depression;
History of any psychotic disorder;
Under-controlled hypertension or diabetes (as reflected by self-report); neurological disease (e.g., multiple sclerosis, epilepsy, amyotrophic lateral sclerosis, Parkinson's disease);
Trial design
Treatments tested in this trial
- alcohol condition
- control condition
Treatment groups
160 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov