Neoantigen Reactive T Cells c for Chinese Patients With Advanced Gastric Cancer

Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-75
SponsorFirst Affiliated Hospital of Wenzhou Medical University

About this trial

The purpose of this study is to see the safety and efficient of neoantigen reactive T cells (NRTs) in the treatment of Chinese patients with advanced gastric cancer.

Eligibility criteria

Qualifiers

Voluntarily join the study and sign the informed consent;

Age: 18-75 years old, male or female;

Subjects with advanced gastric cancer who had received systematic standard treatment before enrollment and had no effective treatment at present. (Note: The effective treatment means refer to the latest version of the "Gastric Cancer Diagnosis and Treatment Guide" issued by China's "Chinese Clinical Oncology Society".) ;

Have at least one measurable lesion according to imRECIST evaluation criteria;

Disqualifiers

Subjects infected with HBV, HCV, HIV, syphilis and tuberculosis;

Uncontrolled coronary artery disease or asthma, uncontrolled cerebrovascular disease or what the investigator considers Other diseases not included in the group;

Patients with a history of bone marrow or organ transplantation; Patients with coagulation dysfunction;

Patients with immune deficiency diseases or autoimmune diseases who are treated with immunosuppressive drugs;

Trial design

Treatments tested in this trial

  • Neoantigen Reactive T Cells(NRTs)

Treatment groups

20 Participants
are divided into 1 treatment group

Locations

This trial has no locations