About this trial
The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate motor modules through human-machine interaction. Ultimately, the development will lead to better clinical motor recovery, better quality of life, and lowered healthcare costs associated with the impairment.
Eligibility criteria
Qualifiers
Hemiparetic chronic stroke survivors more than 6 months after stroke onset
Adults aged 21-80 years, including both female and male participants
Individuals with a single unilateral ischemic or hemorrhagic stroke
Individuals with Upper Extremity Fugl-Meyer Assessment score between 10 and 59 out of 66
Disqualifiers
Individuals younger than 21 years of age or older than 80 years of age
Individuals with an orthopedic disorder involving the upper limbs
Individuals unable to produce voluntary upper-extremity muscle EMG activity;
Individuals with cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol, assessed using the Montreal Cognitive Assessment or other IRB-approved screening procedures.
Trial design
Treatments tested in this trial
- Neuromuscular coordination enhancement (NICE) intervention
- EMG Amplitude Biofeedback Exercise
Treatment groups
Sponsors and collaborators
University of Houston
Lead sponsor
TIRR Memorial Hermann
Collaborator
The University of Texas Health Science Center, Houston
Collaborator