About this trial
The study will test and compare the efficacy of a single essential amino acid valine with a combination of essential amino acids (EAA) supplement on fatigue, frailty, and cognitive function in end-stage kidney disease (ESKD) patients undergoing hemodialysis (HD) treatment.
Eligibility criteria
Qualifiers
Male or Female
Age 18-64 years
Receiving 3 x weekly in clinic hemodialysis for at least 6 months
Disqualifiers
Hypersensitivity to amino acid(s) and/or any excipient
Clinical documentation of COVID-19
Concomitant intake of amino acids supplements
Current use or abuse of alcohol, marijuana, narcotic, or other substances
Trial design
Treatments tested in this trial
- Valine
- EEA
Treatment groups
Sponsors and collaborators
The University of Texas Health Science Center at San Antonio
Lead sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborator
IIMS-UT Health San Antonio
Collaborator