Pharmacokinetics of Oral Calcium Carbonate in Parturients
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorStanford University
About this trial
This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). This information is important for trials investigating whether calcium can reduce postpartum hemorrhage, bleeding after delivery.
Eligibility criteria
Qualifiers
Pregnant female subjects at the study institution, admitted for labor (spontaneous, augmented, or induced)
Disqualifiers
severe range blood pressure (BP >160/>110) within the 48 hours prior to delivery
patient age <18 years or >45 years
renal dysfunction with a documented serum Cr > 1.0 mg/dL
known history of congenital or acquired cardiac disease or history of arrhythmia
Trial design
Treatments tested in this trial
- Oral calcium carbonate
Treatment groups
60 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov