Propranolol in Primary Progressive Aphasia
ConditionAphasia, Primary Progressive
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age50+
SponsorUniversity of Missouri-Columbia
About this trial
The purpose of this study is to find out how the language of people with Primary Progressive Aphasia is affected by Propranolol. Propranolol is not FDA approved for the treatment of Primary Progressive Aphasia. Propranolol is FDA approved for the treatment of heart conditions such as blood pressure.
This research is being done because there are currently no drug treatment options for language impairments and anxiety often experienced by people with Primary Progressive Aphasia.
Eligibility criteria
Qualifiers
1. Age: 50 and older
2. Primary Progressive Aphasia diagnosis
3. Native English speaker
Disqualifiers
1. Unable to provide consent
2. Taking alpha 2 agonists (clonidine and guanfacine)
3. Other major psychological or neurological diagnosis
4. Major head trauma that contributed to their condition
Trial design
Treatments tested in this trial
- Propranolol
- Magnetic Resonance Imaging (MRI)
- Placebo
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov