Prucaloprida vs Bisacodyl as a Stimulant in Bowel Preparation for Video Colonoscopy in Adults

Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorHospital de Clínicas Dr. Manuel Quintela

About this trial

The objective of this randomized clinical trial is to compare prucalopride versus bisacodyl as a stimulant agent for bowel cleansing preparation prior to colonoscopy in patients undergoing the procedure at the Endoscopy Unit of the Hospital de Clínicas. The main research questions this study aims to answer are:

Is prucalopride superior or equivalent to bisacodyl as a stimulant agent for bowel cleansing preparation before colonoscopy? Is the tolerability of prucalopride better, equivalent, or worse compared to bisacodyl? The investigators will compare the standard bowel cleansing preparation using polyethylene glycol (PEG) in combination with either bisacodyl or prucalopride as the stimulant agent.

Participants will be randomized into two groups, both receiving the same base preparation with different stimulant agents.

Eligibility criteria

Qualifiers

All patients over 18 years of age.

Without prior colonic surgical interventions.

Who attend the Digestive Endoscopy service to undergo a colonoscopy.

Disqualifiers

Patients who voluntarily choose not to participate in the study.

Pregnant women.

Patients with rectocolonic resections and/or ileostomies.

Inflammatory bowel disease.

Trial design

Treatments tested in this trial

  • Bisacodyl 5 MG
  • Prucalopride 2mg

Treatment groups

124 Participants
are divided into 2 treatment groups

Locations

This trial has no locations