Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age21-55
SponsorRoswell Park Cancer Institute

About this trial

This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States. Flavors such as menthol play an important role in the start and continued use of tobacco products. Two ways users experience flavor is through smell and taste. Menthol has cooling and numbing properties that can increase perceptions of smoothness and reduce the perceived harshness of smoke. Menthol adds a taste and aroma commonly described as "minty". The effect of menthol flavoring on smoking behavior has been studied. Use of menthol cigarettes has been associated with greater nicotine dependence and is associated with both fewer quit attempts and lower odds of quit success. In 2022, the Food and Drug Administration proposed to restrict the use of menthol as a flavor in cigarettes. Menthol has already been banned in Canada, the United Kingdom and the European Union. In late 2022, a restriction on all flavored tobacco products went into effect in California (CA), prompting the tobacco industry to introduce substitute products that did not contain menthol. It is important to find out whether New York (NY) adult smokers who smoke menthol cigarettes can identify and characterize flavors in the same cigarette brand as sold in NY versus CA following the ban of menthol cigarettes in 2022.

Eligibility criteria

Qualifiers

Aged 21-55 years old

Current daily smoker of factory-made menthol cigarettes

General good health (assessed by self-rated health item)

Completion of Brief Smell Identification Test (B-SIT) with no identification of deficits

Disqualifiers

Daily concurrent use of other tobacco products (e.g., e-cigarettes, cigars, smokeless tobacco)

Known allergies to mint (peppermint, spearmint), menthol

Self-reported olfactory or taste deficits

Pregnant or nursing participants, as indicated by self-report

Trial design

Treatments tested in this trial

  • Cigarette smell test
  • Cigarette Taste Test
  • Study questionnaires

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators