Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-45
SponsorUniversity of Missouri-Columbia
About this trial
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
Eligibility criteria
Qualifiers
BMI >18 kg/m2
Disqualifiers
Pregnancy, breastfeeding
Diagnosed sleep apnea or AHI >10 events/hr
Current smoking/Nicotine use
Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy
Trial design
Treatments tested in this trial
- Propranolol Hydrochloride
- Isoproterenol
- Phentolamine Mesylate
- Norepinephrine
Treatment groups
72 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov