tDCS for Cancer-Related Fatigue and Weakness
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age40-80
SponsorKessler Foundation
About this trial
This pilot study investigates the effectiveness of non-invasive brain stimulation (tDCS) in alleviating cancer-related fatigue (CRF) and muscle weakness. Using a randomized, double-blind crossover design, participants perform fatiguing muscle tasks with and without tDCS, and outcomes include task endurance, maximal voluntary contraction force, and neuromuscular markers. Neural mechanisms will be assessed via EEG, TMS, and MRI.
Eligibility criteria
Qualifiers
Aged 40-80
Right Handed, as determined by the Edinburgh Inventory 21
Proficient in English
Must be available for the familiarization, and testing sessions
Disqualifiers
History of epilepsy or unprovoked seizures
Family history of epilepsy (father, mother, children, siblings with diagnosis of epilepsy)
Active migraine headaches
Past or current history of treated tinnitus or severe hearing problems
Trial design
Treatments tested in this trial
- Active tDCS + elbow flexion exercise
- Sham tDCS + elbow flexion exercise
Treatment groups
75 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov