The Efficacy and Safety of Remimazolam Besylate for Cardiac Anesthesia

ConditionAnesthesia
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-65
SponsorChinese Academy of Medical Sciences, Fuwai Hospital

About this trial

The evidence on the practice of remimazolam besylate during cardiac anesthesia is scarce. This study investigates the efficacy and safety of remimazolam besylate general induction and maintenance during cardiac surgery.

Eligibility criteria

Qualifiers

Elective cardiac surgery via cardiopulmonary bypass;

Aged 18-65 years;

American Society of Anesthesiologists (ASA) grade I-III;

Body mass index (BMI) 18-28 kg/m2.

Disqualifiers

A history of sternotomy for heart disease;

Angina or arrhythmia with severe dynamics flutters pre-operation;

Respiratory, hepatic or renal dysfunction (oxygenation index<300, alanine transaminase> 2 upper limits of normal value, creatinine > 200 μmol/L);

Diagnosed with advanced tumors;

Trial design

Treatments tested in this trial

  • remimazolam besylate
  • propofol

Treatment groups

320 Participants
are divided into 2 treatment groups

Locations

This trial has no locations