To Assess Safety, Tolerability, and Efficacy of Anti-GPRC5D-CD19-CAR-T in Relapsed/Refractory Multiple Myeloma

Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-75
SponsorGuangdong Second Provincial General Hospital

About this trial

To evaluate the safety and tolerability of anti-GPRC5D-CD19 CAR-T cells infusion in subjects with relapsed and refractory multiple myeloma

Eligibility criteria

Qualifiers

1. The patient or their legal guardian understands and voluntarily signs the informed consent form and is expected to complete the follow-up examinations and treatments.

Alanine transaminase (ALT) ≤3 times the upper limit of normal (ULN);

Aspartate transaminase (AST) ≤3 times ULN;

Total bilirubin ≤1.5 times ULN;

Disqualifiers

1. Diagnosed with or treated for invasive malignant tumors other than multiple myeloma.

Trial design

Treatments tested in this trial

  • infusion of GPRC5D-CD19 CAR T injection

Treatment groups

15 Participants
are divided into 1 treatment group