Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age22-33
SponsorWake Forest University Health Sciences

About this trial

The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.

Eligibility criteria

Qualifiers

Singleton birth

Born at less than 34 weeks gestational age (preterm cohort)

Born at greater than 36 weeks gestational age (term cohort)

Disqualifiers

Twin birth

Congenital anomalies or genetic syndromes

Currently pregnant or breast feeding

Subject-reported history of hypertension

Trial design

Treatments tested in this trial

  • Allopurinol
  • Dietary Intervention

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator